Matrigel Scaffolding Enhances BMP9-induced Bone Formation in Dental Follicle Stem/Precursor Cells

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Matrigel Enhances in vitro Bone Differentiation of Human Marrow-derived Mesenchymal Stem Cells

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matrigel enhances in vitro bone differentiation of human marrow-derived mesenchymal stem cells

objective(s) the use of co-culture cells as well as extra cellular matrix are among those strategies that have been employed to direct mesenchymal stem cell (msc) bone differentiation in culture. in this regard, there is no study considering the effects of matrigel on mesenchymal stem cell (msc) in vitro bone differentiation. this was the subject of the present study. materials and methods huma...

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BMP9-Induced Osteogenetic Differentiation and Bone Formation of Muscle-Derived Stem Cells

Efficient osteogenetic differentiation and bone formation from muscle-derived stem cells (MDSCs) should have potential clinical applications in treating nonunion fracture healing or bone defects. Here, we investigate osteogenetic differentiation ability of MDSCs induced by bone morphogenetic protein 9 (BMP9) in vitro and bone formation ability in rabbit radius defects repairing model. Rabbit's ...

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Dental follicle stem cells in bone regeneration on titanium implants

BACKGROUND We aimed to demonstrate that DF stem cells from impacted molars and canines can be used to improve bone regeneration on titanium implants surfaces. This study highlights the presence of stem cells in DF, their potential to adhere and differentiate into osteoblasts on different types of titanium surfaces. RESULTS Isolated cells from the harvested DF tissue from impacted canine/molar...

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The de novo formation of ectopic bone marrow was induced using 1.2-mm-thin polycaprolactone (PCL) scaffolds biomodified with several different biomaterials. In vivo investigations of de novo bone and bone marrow formation indicated that subcutaneous implantation of PCL scaffolds coated with recombinant human bone morphogenetic protein-2 (rhBMP-2) plus Matrigel, hydroxyapatite (HA), or StemRegen...

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ژورنال

عنوان ژورنال: International Journal of Medical Sciences

سال: 2019

ISSN: 1449-1907

DOI: 10.7150/ijms.30801